GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
PHARMACOKINETICS-I/FRL-4010
Course Title: PHARMACOKINETICS-I
Credits 3 ECTS 9
Course Semester 2 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Teaches the clinical importance of concentration-time and concentration-effect relationships
Gets familiar with the terms and concepts of drug absorption and distribution
Gets familiar with the terms and concepts of drug elimination
Can analyze compartment models
Learns the details of using pharmacokinetic knowledge in clinical applications.
Learns lineer regression and calculation of the slope
Can calculate absorption and elimination rate constants in one compartment open model
Can calculate distribution volume in one compartment open model
Can calculate bioavailability in one compartment open model
Can calculate clearance in one compartment open model

 -- MODE OF DELIVERY
  face to face
 --WEEKLY SCHEDULE
1. Week  Terms and definitions in pharmacokinetics, clinical importance of time-concentration and concentration-effect relationships
2. Week  Exponential functions, logarithms, integral and differantiation in pharmacokinetic calculations, Zero-order and first-order kinetics
3. Week  Graphic usage in pharmacokinetics, lineer regression, calculation of the slope
4. Week  Compartment models in pharmacokinetics and related equations
5. Week  Calculation of pharmacokinetic variables of i.v. administration in one-compartmental open model
6. Week  Examples for i.v. administration in one-compartmental open model
7. Week  Examples for i.v. administration in one-compartmental open model
8. Week  Calculation of pharmacokinetic variables of extravascular drug administration in one-compartmental open model
9. Week  Estimation of absorption rate constant
10. Week  Examples for extravascular drug administration in one-compartmental open model
11. Week  Examples for extravascular drug administration in one-compartmental open model
12. Week  Examples for extravascular drug administration in one-compartmental open model
13. Week  Concepts and definitions about bioequivalance and bioavailability, importance in drug therapy
14. Week  Examples on bioavailability calculations
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
30
 Assignment
1
10
 Application
1
10
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
3
42
 Weekly Tutorial Hours
14
0
0
 Reading Tasks
0
 Searching in Internet and Library
14
4
56
 Material Design and Implementation
14
4
56
 Report Preparing
0
 Preparing a Presentation
0
 Presentation
0
 Midterm Exam and Preperation for Midterm Exam
14
2
28
 Final Exam and Preperation for Final Exam
14
3
42
 Other (should be emphasized)
1
1
1
 TOTAL WORKLOAD: 
225
 TOTAL WORKLOAD / 25: 
9
 Course Credit (ECTS): 
9
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4X
5X
6X
7X
8X
9X
10X
11X
12X
13X
14X
 -- NAME OF LECTURER(S)
   (Prof. Dr. H. Zafer Güney , Prof. Dr. Canan Uluoğlu , Prof. Dr. Süreyya Barun , Prof. Dr. Çimen Karasu , Assoc. Prof. Sevil Özger İlhan , Assoc. Prof. Ergin Dileköz , Assoc. Prof. Gökçe Sevim Öztürk Fincan)
 -- WEB SITE(S) OF LECTURER(S)
   (websitem.gazi.edu.tr/site/zguney)
 -- EMAIL(S) OF LECTURER(S)
   (zguney@gazi.edu.tr)