GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
ENZYME KINETICS/EBY-6030
Course Title: ENZYME KINETICS
Credits 2 ECTS 5
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
To learn how enzymes work
Understanding reaction kinetics of enzymes
To learn the role of enzyme structure in activity
To learn kinetic calculations of enzymes

 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face
 --WEEKLY SCHEDULE
1. Week  Introduction to Enzyme Kinetics Basic principles of chemical kinetics
2. Week  Thermodynamic laws, equilibrium and types of reaction
3. Week  Mechanisms of enzymatic catalysis, activation energy
4. Week  The effects of several factors on velocity of enzymatic reactions
5. Week  Kinetics of enzymes catalyzing one-substrate reactions, Michaelis-Menten equation
6. Week  Lineweaver-Burk and Eadie-Hofstee equations
7. Week  Kinetics of enzymes catalyzing multi-substrate reactions
8. Week  Inhibition of non-cooperative enzymes
9. Week  Kinetic of allosteric enzymes
10. Week  Sigmoidal kinetics of cooperative allosteric enymes, importance of sigmoidal action, Hill equation
11. Week  Determination of enzyme activity-1: End-point analysis
12. Week  Determination of enzyme activity-2: Kinetic methods
13. Week  Enzyme Kinetic Problems-1 Enzim Kinetiği Problemi
14. Week  Enzyme Kinetic Problems-2
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
80
 Assignment
1
20
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
40
 Percentage of Final Exam to Total Score  
60
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
0
 Searching in Internet and Library
13
2
26
 Material Design and Implementation
0
 Report Preparing
2
4
8
 Preparing a Presentation
2
5
10
 Presentation
2
2
4
 Midterm Exam and Preperation for Midterm Exam
1
19
19
 Final Exam and Preperation for Final Exam
1
30
30
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
125
 TOTAL WORKLOAD / 25: 
5
 Course Credit (ECTS): 
5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2
3X
4X
5
6
7
8
9
10X
11
12
 -- NAME OF LECTURER(S)
   (Prof.Sevgi AKAYDIN)
 -- WEB SITE(S) OF LECTURER(S)
   (http://www.websitem.gazi.edu.tr/site/sevgiy)
 -- EMAIL(S) OF LECTURER(S)
   (sevgiy@gazi.edu.tr)