GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
THERAPEUTIC DRUG MONITORING/FRL-5120
Course Title: THERAPEUTIC DRUG MONITORING
Credits 3 ECTS 9
Course Semester 3 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
1. Knowledge basis: • To define therapeutic drug monitoring (TDM) • To explain the rationale (goals) of TDM.
2. Skills basis : • To be validation of the method • To extract of one drug from plasma • Perform a drug analysis with HPLC
3. Attitude basis: • To be aware of the importance of TDM for the drugs with a narrow therapeutic window and the higher potency of toxic effect
 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face
 --WEEKLY SCHEDULE
1. Week  Theoretical: objectives and implementation of TDM
2. Week  Theoretical: Why TDM? Examples and principles of drugs that are monitored by TDM
3. Week  Theoretical: Pharmacokinetic parameters and the use for TDM
4. Week  Theoretical: The rules and guidelines on the implementation of TDM (FDA and the EMA rules)
5. Week  Practical: discussion of the cases
6. Week  Theoretical: HPLC and operating principles
7. Week  Practical: the use of HPLC
8. Week  Practical: the use of HPLC
9. Week  Visit to Novagenix
10. Week  Methods of determination 0f pharmaceutical active compounds and / or metabolites in physiological fluids and validation of methods
11. Week  Practical: Extraction of the drug from plasma
12. Week  Practical: To obtain the calibration curve using HPLC
13. Week  Practical: Calculate the value of CV
14. Week  Interpretation of the test results and report preparation
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
30
 Assignment
0
0
 Application
0
0
 Projects
0
0
 Practice
1
10
 Quiz
0
0
 Percent of In-term Studies  
40
 Percentage of Final Exam to Total Score  
60
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
3
42
 Weekly Tutorial Hours
0
 Reading Tasks
8
2
16
 Searching in Internet and Library
5
4
20
 Material Design and Implementation
10
4
40
 Report Preparing
10
4
40
 Preparing a Presentation
5
4
20
 Presentation
1
3
3
 Midterm Exam and Preperation for Midterm Exam
10
2
20
 Final Exam and Preperation for Final Exam
10
2
20
 Other (should be emphasized)
4
1
4
 TOTAL WORKLOAD: 
225
 TOTAL WORKLOAD / 25: 
9
 Course Credit (ECTS): 
9
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1
2
3
4X
5X
6X
7
8X
9
10
11X
12
13X
14X
 -- NAME OF LECTURER(S)
   (All faculty members of the Department of Medical Pharmacology)
 -- WEB SITE(S) OF LECTURER(S)
   ()
 -- EMAIL(S) OF LECTURER(S)
   (culuoglu@yahoo.com cimenkrs@gmail.com zaferguney@yahoo.com sbarun99@hotmail.com edilekoz@gmail.com soilhan@Hotmail.com gokcesevimozturk@hotmail.com )