GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
Protein and Nucleic Acid/TBG-2020
Course Title: Protein and Nucleic Acid
Credits 2 ECTS 6
Semester 1 Compulsory/Elective Elective
COURSE INFO
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- NAME OF LECTURER(S)
  Prof. Ece KONAC, Assoc. Prof. Hacer Ilke ONEN, Assoc. Prof. Atiye Seda YAR SAGLAM
 -- WEB SITE(S) OF LECTURER(S)
  http://www.websitem.gazi.edu.tr/site/ecem, http://www.websitem.gazi.edu.tr/site/hionen, http://www.websitem.gazi.edu.tr/site/sedayar
 -- EMAIL(S) OF LECTURER(S)
  ecem@gazi.edu.tr, hionen@gazi.edu.tr,sedayar@gazi.edu.tr
 -- LEARNING OUTCOMES OF THE COURSE UNIT
To be able to understand the relationship between nucleic acids and proteins.
To be able to explain the structures that nucleic acid and protein co-existence occurs.
To be able to understand the functional importance of nucleic acid-protein co-existence in the cell.






 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face
 -- PREREQUISITES AND CO-REQUISITES
  There is no prerequisite or co-requisite for this course
 -- RECOMMENDED OPTIONAL PROGRAMME COMPONENTS
  There is no recommended optional programme component for this course
 --COURSE CONTENT
1. Week  General knowledge about nucleic acids
2. Week  General knowledge about proteins
3. Week  Proteins that bind to DNA and DNA-binding domains
4. Week  Proteins that bind to RNA and DNA-binding domains
5. Week  Nucleosomes structure and histone variants
6. Week  Telomerase structure and function
7. Week  Ribosomes structure and function
8. Week  Proteasome structure and function
9. Week  Midterm
10. Week  Peptide nucleic acids and evolution
11. Week  RNA interferance
12. Week  Biogenesis, maturation and function of miRNA
13. Week  The role of miRNAs in human diseases
14. Week  The role of miRNAs in human diseases
15. Week  CRISPR-CAS9 system
16. Week  Final exam
 -- RECOMMENDED OR REQUIRED READING
  Bruce Alberts, Molecular biology of the cell Geoffrey M. Cooper, The Cell: A Molecular Approach
 -- PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
  Lecture, Question & Answer
 -- WORK PLACEMENT(S)
  N/A
 -- ASSESSMENT METHODS AND CRITERIA
 
Quantity
Percentage
 Mid-terms
1
40
 Assignment
1
10
 Exercises
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Contribution of In-term Studies to Overall Grade  
50
 Contribution of Final Examination to Overall Grade  
50
 -- WORKLOAD
 Efficiency  Total Week Count  Weekly Duration (in hour)  Total Workload in Semester
 Theoretical Study Hours of Course Per Week
16
2
32
 Practising Hours of Course Per Week
0
 Reading
16
3
48
 Searching in Internet and Library
16
2
32
 Designing and Applying Materials
0
 Preparing Reports
0
 Preparing Presentation
4
1
4
 Presentation
1
2
2
 Mid-Term and Studying for Mid-Term
9
2
18
 Final and Studying for Final
7
2
14
 Other
0
 TOTAL WORKLOAD: 
150
 TOTAL WORKLOAD / 25: 
6
 ECTS: 
6
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1- Understanding of basic concepts in genetics ,application of genetic information in diagnosis and monitoring the course of human diseases,application of genetic technologies in medicine,advanced molecular genetics,cellular biology,molecular biology of human neoplastic diseases.X
2Learning structures of cell membranes and organelles in detail at the molecular level.X
3Learning basic rules of patterns of inheritance and pedigree analysis.X
4Knowing chemical and physical properties of DNA, RNA and proteins.X
5Becoming familiar with new instruments and technologies that are required to do an experimental research in the cell and molecular biology labs.X
6Learns the basic molecules which are responsible for the storage and duplication of genetic information and its transfer into proteins .X
7Gets acquainted with molecular biology focusing on gene transcription and protein-protein interactionsX
8Acquaring skills of DNA and RNA isolation, quantitating DNA or RNA, PCR, electrophoresis, RT-PCR, cell culture.X
9Understanding the roles of genetic and epigenetic mechanisms observed in genes in the process of evolution and transmit of hereditary features and disorders from one generation to another.X
10Learns the meaning of genetic code and its role in the relationship between the structure and function of organisms.X