GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
PHARMACOKINETICS-II/TFRL-6040
Course Title: PHARMACOKINETICS-II
Credits 3 ECTS 9
Course Semester 3 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Gets familiar with the methods for modelling and calculation of pharmacokinetic variables via concentration-time graphics
Can calculate pharmacokinetic variables such as absorption rate constant, elimination rate constant and half life, clearance, distribution volume in t
Can calculate pharmacokinetic variables such as absorption rate constant, elimination rate constant and half life, clearance, distribution volume in t
Gets familiar with "sigma minus" and "method of residuals"
Learns the usage of pharmacokinetic knowledge in clinical applications
Learns estimation of dosage and infusion rate for i.v. infusion
Learns how to estimate elimination rate constant from urine data
Learns the calculation of pharmacological variables in multidosage regimens
Gets familiar with dosage adjustement in renal impairment
Can discuss the relationship between pharmacokinetics and pharmacological response
 -- MODE OF DELIVERY
  Face to face
 --WEEKLY SCHEDULE
1. Week  Multicompartment models, Method of residuals
2. Week  Calculation of pharmacokinetic variables in two compartment model- i.v. route
3. Week  Examples on the calculation of pharmacokinetic variables in two compartment model- i.v. route
4. Week  Calculation of pharmacokinetic variables in two compartment model- p.o. route
5. Week  Gains competancy in usage of pharmacokinetic knowledge in clinical applications
6. Week  Calculation of pharmacokinetic variables in three compartment model- i.v. route
7. Week  Calculation of pharmacokinetic variables in three compartment model- p.o. route
8. Week   Estimation of dosage and infusion rate for i.v. infusion
9. Week   Estimation of the elimination rate constant from urine data
10. Week   Estimation of pharmacological variables in multidosage regimens
11. Week  Constant dose-constant interval drug administration
12. Week   Dosage adjustement in renal impairment, Giusti-Hayton Method and Wagner Method
13. Week   Clinical pharmacokinetic applications in renal disease
14. Week  Relationship between pharmacokinetics and pharmacological response
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
30
 Assignment
1
20
 Application
1
10
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
3
42
 Weekly Tutorial Hours
0
 Reading Tasks
14
4
56
 Searching in Internet and Library
14
2
28
 Material Design and Implementation
12
4
48
 Report Preparing
0
0
0
 Preparing a Presentation
0
0
0
 Presentation
0
0
0
 Midterm Exam and Preperation for Midterm Exam
10
2
20
 Final Exam and Preperation for Final Exam
10
3
30
 Other (should be emphasized)
1
1
1
 TOTAL WORKLOAD: 
225
 TOTAL WORKLOAD / 25: 
9
 Course Credit (ECTS): 
9
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4X
5X
6X
7X
8X
9X
10X
11X
12X
13X
14X
 -- NAME OF LECTURER(S)
   (Prof. Dr. H. Zafer Güney , Prof. Dr. Canan Uluoğlu , Prof. Dr. Süreyya Barun , Prof. Dr. Çimen Karasu , Assoc. Prof. Sevil Özger İlhan , Assoc. Prof. Ergin Dileköz , Assoc. Prof. Gökçe Sevim Öztürk Fincan)
 -- WEB SITE(S) OF LECTURER(S)
   (www.gazi.edu.tr/zguney)
 -- EMAIL(S) OF LECTURER(S)
   (zguney@gazi.edu.tr)