GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
IMMUNOPHARMACOLOGY/TFRL-5090
Course Title: IMMUNOPHARMACOLOGY
Credits 2 ECTS 6
Course Semester 3 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  English
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Students will have knowledge on basic immunopharmacology beginning with innate immune responses followed by a study of aspects of acquired immunity.
To define molecular structure of B and T cell antigen receptors, signaling through immune receptors.
To explain the mediators of acute and chronic inflammation; specific roles for some cytokines/lymphokines.
To explain microbial immunity and related drugs.
To define allergy, autoimmunity and anti-allergic agents.
To define tumor immunology, immunotherapeutics and new drug targets.
Students will have knowledge about congenital and acquired immunodeficiencies.
To define transplantation immunology and immunosupressive drugs.
To define the mechanisms of autoimmune diabetes mellitus and drug targets linked with autoimmun diseases.
Student will be able to explain the mechanism of action of new chemical and natural agents potentially controling the inflammatory process.

 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face.
 --WEEKLY SCHEDULE
1. Week  The principles of Immunopharmacology and immunotoxicology
2. Week  Hematopoiesis and lymphocyte development: an introduction. Immunopharmacology and hematopoiesis.
3. Week  Blood cell development and immunity.
4. Week  T cell subsets and T cell-mediated immunity. Effectors of T cell-mediated immunity. Antibody diversity and B lymphocyte-mediated immunity.
5. Week  Biological functions of antibodies: Clinical relevance and future prospects.
6. Week  Dendritic cells: Pathophysiological relevance and Pharmacological implications.
7. Week  Innate immunity – Phagocytes, natural killer cells and the complement system.
8. Week  Cytokines,Chemokines, Mediators of inflammation. Regulatory factors of immune reactions.
9. Week  Inflammatory mediators and intracellular signalling: Eicosanoids, Platelet-activating factor, Innate immune signalling receptors.
10. Week  Inflammatory mediators and intracellular signalling: Cytokines, Chemokines, Neuropeptides, Kinins, Amines.
11. Week  Inflammatory mediators and intracellular signalling: Nitric oxide, Reactive oxygen species.
12. Week  Pathogenesis of shock: Human immunodeficiency virus infection. Vaccines and vaccination.
13. Week  Neuroimmunoendocrinology: Functions of leukocyte-derived peptide hormones in vivo. Regulation of nervous system by immune factors.
14. Week  Cancer immunity, Immunotherapy of cancer.Immunostimulants in cancer therapy. Natural and synthetic biological response modifiers.
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
70
 Assignment
1
20
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
1
10
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
14
1
14
 Searching in Internet and Library
14
2
28
 Material Design and Implementation
0
 Report Preparing
0
 Preparing a Presentation
14
0
0
 Presentation
14
1
14
 Midterm Exam and Preperation for Midterm Exam
14
2
28
 Final Exam and Preperation for Final Exam
14
2
28
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
140
 TOTAL WORKLOAD / 25: 
5.6
 Course Credit (ECTS): 
6
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3
4X
5
6X
7
8X
9X
10
11
12
13X
14X
 -- NAME OF LECTURER(S)
   (All faculty members of the pharmacology department.)
 -- WEB SITE(S) OF LECTURER(S)
   (https://websitem.gazi.edu.tr/site/barun)
 -- EMAIL(S) OF LECTURER(S)
   (barun@gazi. edu.tr; sbarun99@gazi.edu.tr)