GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
ENZYME KINETICS/BYO-6260
Course Title: ENZYME KINETICS
Credits 2 ECTS 8
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Learns the role of enzymes in metabolic reactions.
Learns the importance of the catalytic efficiency of enzymes.
Learns the equations related to enzyme kinetics.
Learns the importance of Km.
Learns the effect of product formation on the rate of the reaction.
Learns how to evaluate kinetic data.
Learns how to use velocity versus substrate concentration curves.
Learns the conditions inhibiting enzyme activities.
Learns the factors affecting the enzyme activities.
Learns how to design an enzyme assay.
 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face
 --WEEKLY SCHEDULE
1. Week  Enzymes as Biological Catalysts
2. Week  Factors Responsible for the Catalytic Efficiency of Enzymes
3. Week  Enzyme Kinetics-Henri, Michaelis and Menten Equation
4. Week  Enzyme Kinetics-Briggs and Haldane Equation
5. Week  Why Determine Km?-Haldane Relationship between Kinetic Constants and Equilibrium Constant
6. Week  Reversible Reactions:Effect of Product on Forward Velocity
7. Week  Velocity versus Substrate Concentration Curves
8. Week  Reaction Order: First Order Kinetics-Zero Order Kinetics
9. Week  Methods of Plotting Enzyme Kinetics Data
10. Week  Enzyme Inhibition
11. Week  Effect of Ph on Enzyme Stability and Activity
12. Week  Effect of Temperature on Enzyme Stability and Activity
13. Week  Enzyme Assays
14. Week  Multisite and Allosteric Enzymes
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
40
 Assignment
0
0
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
40
 Percentage of Final Exam to Total Score  
60
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
6
4
24
 Searching in Internet and Library
10
5
50
 Material Design and Implementation
0
 Report Preparing
0
 Preparing a Presentation
8
5
40
 Presentation
1
2
2
 Midterm Exam and Preperation for Midterm Exam
5
3
15
 Final Exam and Preperation for Final Exam
8
2
16
 Other (should be emphasized)
8
3
24
 TOTAL WORKLOAD: 
199
 TOTAL WORKLOAD / 25: 
7.96
 Course Credit (ECTS): 
8
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4X
5X
6X
7X
8X
9X
10X
 -- NAME OF LECTURER(S)
   (Prof. Dr. Nedret KILIÇ)
 -- WEB SITE(S) OF LECTURER(S)
   (www.gazi.edu.tr)
 -- EMAIL(S) OF LECTURER(S)
   (nedretk@gazi.edu.tr , nedretkilic73@gmail.com)