GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
CHRONOPHARMACOLOGY/FRL-5050
Course Title: CHRONOPHARMACOLOGY
Credits 3 ECTS 9
Course Semester 2 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Understands the importance of biological rhythms in drug effect
Gets familiar with the relationships between biological rhythms and manifestation of diseases
Gets familiar with the concepts and underlying mechanisms of chronopharmacokinetics, chronesthesy, chronergy and chronotoxicity
Learns the principles of chronotherapy and its current applications
Gains competency on the importance of drug administration time in clinical settings
Learns chronobiology of cardiovasculary system and chronopharmacology of cardiovasculary diseases
Learns chronobiology of respiratory system and chronopharmacology of related diseases
Learns chronobiology of depression and chronopharmacology of related therapeutic approaches
Learns chronobiology of pain and chronopharmacology of related drugs
Learns chronobiology of sleep and chronopharmacology of sleep disorders

 -- MODE OF DELIVERY
  face to face lecturing
 --WEEKLY SCHEDULE
1. Week  Biological rhythms and their general properties, The clock, pineal gland and neuronal innervation
2. Week  Melatonin : hormone and drug
3. Week  Importance of biological rhythms in drug effect, terms and definitions in chronopharmacology, graphics and statistical approaches for curvilineer data
4. Week  Chronopharmacokinetics
5. Week  Rhythms in second messenger mechanisms
6. Week  Biological rhythms and disease symptoms
7. Week  Principles in chronotherapy and current applications
8. Week  Chronotherapy in nocturnal asthma
9. Week  Chronobiology of cardiovasculary system and chronopharmacology of cardiovasculary diseases
10. Week  Chronobiology and chronopharmacology of haemopoetic and haemostatic systems
11. Week  Circadian rhythms and depression, light therapy in seasonal affectif disorder
12. Week  Biological rhythms in pain and analgesia
13. Week  Effect of drugs on biological rhythms
14. Week  Chronotoxicity
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
20
 Assignment
0
0
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
20
 Percentage of Final Exam to Total Score  
80
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
3
42
 Weekly Tutorial Hours
0
 Reading Tasks
14
5
70
 Searching in Internet and Library
14
4
56
 Material Design and Implementation
0
 Report Preparing
0
 Preparing a Presentation
0
 Presentation
0
 Midterm Exam and Preperation for Midterm Exam
12
1
12
 Final Exam and Preperation for Final Exam
14
3
42
 Other (should be emphasized)
1
3
3
 TOTAL WORKLOAD: 
225
 TOTAL WORKLOAD / 25: 
9
 Course Credit (ECTS): 
9
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4
5X
6X
7
8X
9X
10
11
12
13X
14X
 -- NAME OF LECTURER(S)
   (ALL FACULTY OF MEDICINE PHARMACOLOGY)
 -- WEB SITE(S) OF LECTURER(S)
   ()
 -- EMAIL(S) OF LECTURER(S)
   (culuoglu@yahoo.com cimenkrs@gmail.com zaferguney@yahoo.com sbarun99@hotmail.com edilekoz@gmail.com soilhan@Hotmail.com gokcesevimozturk@hotmail.com )