GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION

MOLECULAR TOXICOLOGY II/FTO-3090

COURSE INFORMATION

-- (CATALOG CONTENT)

-- (TEXTBOOK)

-- (SUPPLEMENTARY TEXTBOOK)

-- (PREREQUISITES AND CO-REQUISITES)

-- LANGUAGE OF INSTRUCTION

Turkish and Eng

-- COURSE OBJECTIVES

-- COURSE LEARNING OUTCOMES

To know how these principles use in toxicology science. Thanks to bioinformatics, to reach easily information belonging

-- MODE OF DELIVERY

The mode of delivery of this course is Face to face

--WEEKLY SCHEDULE
1. Week	Molecular toxicology and basic concepts in genetics
2. Week	Genetic organisation (from DNA to RNA, frm RNA to protein)
3. Week	Proteomics (protein expression) and general strategy in proteome analysis
4. Week	Toxicoproomics in drug discovery and developments, toxicoproteomic-adverse drug reactions
5. Week	Disease specific proteins in certain diseases (gene-enironment, gene-disease)
6. Week	Changes on gene expression of DNA repair proteins (BER, NER etc.) in toxicity and disease (Biomarker of Exposure)
7. Week	Metabolomics and its applications, the effects of toxic substances on phenotype
8. Week	Application of metabolomics in clarifying action mechanism of toxicity and analytical technique
9. Week	Presentation and homework
10. Week	Introduction to bioinformatics, descriptions of some concepts with examples
11. Week	Data bases for accessing information about a gene how to use, method creation (primary) design, enzyme selection, etc.)
12. Week	Data from NCBI database for nucleeicacid and protein gene sequences
13. Week	Gene expression database I (EMBL; European Molecular Biology Laboratory, NCGR, National Center for Genome Resources, GEO,Gen Expression Omnibus vs.)
14. Week	Discussion on advantages of omics Technologies and bioinformatics (Where we are and where we must ) to toxicology science
15. Week
16. Week

-- TEACHING and LEARNING METHODS

-- ASSESSMENT CRITERIA

	Quantity	Total Weighting (%)
Midterm Exams	1	25
Assignment	1	25
Application	0	0
Projects	0	0
Practice	0	0
Quiz	0	0

Percent of In-term Studies		50
Percentage of Final Exam to Total Score		50

-- WORKLOAD

Activity	Total Number of Weeks	Duration (weekly hour)	Total Period Work Load
Weekly Theoretical Course Hours	14	3	42
Weekly Tutorial Hours			0
Reading Tasks	2	10	20
Searching in Internet and Library	2	10	20
Material Design and Implementation			0
Report Preparing	2	10	20
Preparing a Presentation	2	10	20
Presentation	2	9	18
Midterm Exam and Preperation for Midterm Exam	1	18	18
Final Exam and Preperation for Final Exam	1	30	30
Other (should be emphasized)			0
TOTAL WORKLOAD:			188
TOTAL WORKLOAD / 25:			7.52
Course Credit (ECTS):			7.5

-- COURSE'S CONTRIBUTION TO PROGRAM

-- NAME OF LECTURER(S)

(. Prof. Dr. Bensu Karahalil )

-- WEB SITE(S) OF LECTURER(S)

(https://websitem.gazi.edu.tr/site/bensu)

-- EMAIL(S) OF LECTURER(S)

(bensu@gazi.edu.tr)

Gazi University