GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
PRACTICE IN GENOTOXICITY/FTO-3081
Course Title: PRACTICE IN GENOTOXICITY
Credits 3 ECTS 7.5
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
To know DNA and chromosomes as the geentic material of the organism
To be able to decide which tests can be used for likely genotoxicity investigation of chemical and physical substance exposure.
To be able to handle cell culture procedures and biological sampling to carry out genotoxicity tests.
To be able to practise the genotoxicity tests
To gain competence in the practice of genotoxicity tests which are in use from regulations to the biomonitoring studies
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face
 --WEEKLY SCHEDULE
1. Week  Description of genotoxicity and DNA damage types
2. Week  In vivo, in vitro experimental conditions and cell culture medium preparation
3. Week  Cell types used in genotoxicity testing
4. Week  Image analysis and evaluation methods of microlesions and macrolesions
5. Week  Chromosome structure and chromosome isolation
6. Week  Numerical and structural khromosomal aberrations
7. Week  Chromosomal aberration and sister chromatid exchange assays
8. Week  Mid term exam
9. Week  Comet assay (Single cell gel electrophoresis technique) I-Practice
10. Week  Comet assay II-Image analysis
11. Week  Practice and evaluation of micronucleus assay in theperipheral blood lymphocytes
12. Week  Practice and evaluation of micronucleus assay in exfoliated epithelial cells
13. Week  Use of short term tests in clinic and regulations
14. Week  Use of short term tests in molecular epidemiology biomonitoring studies
15. Week  Student practice and presentation in laboratory
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
25
 Assignment
1
25
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
0
0
0
 Weekly Tutorial Hours
14
3
42
 Reading Tasks
2
10
20
 Searching in Internet and Library
2
10
20
 Material Design and Implementation
0
0
0
 Report Preparing
2
10
20
 Preparing a Presentation
2
10
20
 Presentation
2
9
18
 Midterm Exam and Preperation for Midterm Exam
1
18
18
 Final Exam and Preperation for Final Exam
1
30
30
 Other (should be emphasized)
0
0
0
 TOTAL WORKLOAD: 
188
 TOTAL WORKLOAD / 25: 
7.52
 Course Credit (ECTS): 
7.5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4X
5X
6X
7X
8X
9X
10X
11X
12
13X
14X
15X
 -- NAME OF LECTURER(S)
   (Prof. Dr. Gonca ÇAKMAK , Prof. Dr. Bensu KARAHALİL)
 -- WEB SITE(S) OF LECTURER(S)
   ()
 -- EMAIL(S) OF LECTURER(S)
   (gcakmak@gazi.edu.tr , bensuka@gmail.com)