GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION

MECHANISM OF ACTION AND SYNTHESIS OF NEW MOLECULAR ENTITIES/FKİ-6040

Course Title:	MECHANISM OF ACTION AND SYNTHESIS OF NEW MOLECULAR ENTITIES
Credits	2	ECTS	5
Course Semester	1	Type of The Course	Elective

COURSE INFORMATION

-- (CATALOG CONTENT)

-- (TEXTBOOK)

-- (SUPPLEMENTARY TEXTBOOK)

-- (PREREQUISITES AND CO-REQUISITES)

-- LANGUAGE OF INSTRUCTION

Turkish

-- COURSE OBJECTIVES

-- COURSE LEARNING OUTCOMES

Have gained knowledge about mechanism of actions of new molecular entities.
Be able to understand synthesis methods of new molecular entities
Have gained knowledge about recent drug targets.
Be able to follow recent developments in medicinal chemistry.
Be able to make literature search and presentation on related subject.

-- MODE OF DELIVERY

Face to face

--WEEKLY SCHEDULE
1. Week	Bedaquiline; Mycobacterial ATP synthase inhibitor
2. Week	Canagliflozin, Dapagliflozin; SGLT2 inhibitor
3. Week	Macitentan; ET receptor antagonist - Riociguat; sGC stimulator
4. Week	Pomalidomide; Anti-angiogenic, Immunomodulator
5. Week	Tasimelteon; Melatonin receptor agonist
6. Week	Afatinib, Ponatinib, Cabozantinib, Axitinib; Tyrosine kinase inhibitors
7. Week	Apremilast; PDE4 inhibitor
8. Week	Elvitegravir, Dolutegravir; HIV integrase inhibitor
9. Week	Sofosbuvir ; HCV NS5B RNA-dependent RNA polymerase inhibitor Simeprevir; HCV protease inhibitor
10. Week	Teriflunomide, Leflunomide; Dihydroorotate dehydrogenase inhibitor
11. Week	Avanafil; PDE5 inhibitor
12. Week	Alogliptin; DPP-4 inhibitor
13. Week	Azilsartan ; Angiotensin II receptor blocker
14. Week	Apixaban; Direct factor Xa inhibitor and student presentations
15. Week
16. Week

-- TEACHING and LEARNING METHODS

-- ASSESSMENT CRITERIA

	Quantity	Total Weighting (%)
Midterm Exams	1	60
Assignment	1	40
Application	0	0
Projects	0	0
Practice	0	0
Quiz	0	0

Percent of In-term Studies		50
Percentage of Final Exam to Total Score		50

-- WORKLOAD

Activity	Total Number of Weeks	Duration (weekly hour)	Total Period Work Load
Weekly Theoretical Course Hours	14	2	28
Weekly Tutorial Hours			0
Reading Tasks	12	1	12
Searching in Internet and Library	6	2	12
Material Design and Implementation			0
Report Preparing	7	2	14
Preparing a Presentation	10	2	20
Presentation	1	1	1
Midterm Exam and Preperation for Midterm Exam	6	3	18
Final Exam and Preperation for Final Exam	4	4	16
Other (should be emphasized)			0
TOTAL WORKLOAD:			121
TOTAL WORKLOAD / 25:			4.84
Course Credit (ECTS):			5

-- COURSE'S CONTRIBUTION TO PROGRAM

NO	PROGRAM LEARNING OUTCOMES	1	2	3	4	5
1						X
2					X
3						X
4					X
5					X
6					X
7				X
8				X
9			X
10				X
11						X
12				X
13				X
14						X
15			X
16					X

-- NAME OF LECTURER(S)

(Assoc.Prof. Burcu Çalışkan)

-- WEB SITE(S) OF LECTURER(S)

(http://websitem.gazi.edu.tr/site/bcaliskan)

-- EMAIL(S) OF LECTURER(S)

(bcaliskan@gazi.edu.tr)

Gazi University

Information Package

Programme Information

Search

GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR