GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
MOLECULAR MODELING APPLICATIONS/FKİ-6060
Course Title: MOLECULAR MODELING APPLICATIONS
Credits 2 ECTS 5
Course Semester 1 Type of The Course Compulsory
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Have gained information about molecular modeling techniques used in drug design and development process.
Be able to apply and evaluate basic molecular modeling techniques.
Appreciate the importance of molecular modeling studies in drug design and development.
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face
 --WEEKLY SCHEDULE
1. Week  Introduction to molecular modeling methods
2. Week  3D visualution of molecules, calculating potential energies
3. Week  X-ray databases, general description and realibility of pdb files
4. Week  Structural properties of amino acids, analysis of active site properties in protein structure
5. Week  Ligand and receptor based molecular modeling studies: general information and case studies
6. Week  Homology modeling
7. Week  Midterm exam
8. Week  Molecular docking studies
9. Week  Evaluating the result of molecular modeling studies
10. Week  Fragment based drug design and success stories
11. Week  Pharmacophore analysis and pharmacophore mapping
12. Week  Virtual screening protocol and success stories
13. Week  Molecular dynamic studies
14. Week  2D and 3D Quantitative structure-activity relationship studies: general information and case studies
15. Week  ComFA and ComSIA models
16. Week  Final exam
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
60
 Assignment
1
10
 Application
1
30
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
0
0
 Reading Tasks
6
3
18
 Searching in Internet and Library
5
3
15
 Material Design and Implementation
0
0
0
 Report Preparing
3
5
15
 Preparing a Presentation
2
3
6
 Presentation
1
2
2
 Midterm Exam and Preperation for Midterm Exam
2
5
10
 Final Exam and Preperation for Final Exam
3
7
21
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
115
 TOTAL WORKLOAD / 25: 
4.6
 Course Credit (ECTS): 
5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4X
5X
6X
7X
8X
9X
10X
11
12
13
14X
15X
16X
 -- NAME OF LECTURER(S)
   (Assoc. Prof. Gokcen EREN)
 -- WEB SITE(S) OF LECTURER(S)
   (https://abs.gazi.edu.tr/gokcene)
 -- EMAIL(S) OF LECTURER(S)
   (gokcene@gazi.edu.tr)