GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION

NONLINEAR PHARMACOKINETICS/FTE-3060

Course Title:	NONLINEAR PHARMACOKINETICS
Credits	2	ECTS	7
Semester	1	Compulsory/Elective	Elective

COURSE INFO

-- LANGUAGE OF INSTRUCTION

Turkish

-- NAME OF LECTURER(S)

Assoc.Prof.Zeynep Şafak TEKSİN, Assoc.Prof.Tuba İnceçayır

-- WEB SITE(S) OF LECTURER(S)

http://websitem.gazi.edu.tr/site/zsteksin, http://www.websitem.gazi.edu.tr/site/tincecayir

-- EMAIL(S) OF LECTURER(S)

zsteksin@gazi.edu.tr, tincecayir@gazi.edu.tr

-- LEARNING OUTCOMES OF THE COURSE UNIT

Understanding the importance, fundamentals and basic concepts of nonlinear pharmacokinetics
Investigation of the nonlinear drugs and dose-response relationship
Learning of the nonlinear models

-- MODE OF DELIVERY

The mode of delivery of this course is Face to face

-- PREREQUISITES AND CO-REQUISITES

There is no prerequisite or co-requisite for this course.

-- RECOMMENDED OPTIONAL PROGRAMME COMPONENTS

There is no recommended optional programme component for this course.

--COURSE CONTENT
1. Week	Definition of nonlinearity, recognition of nonlinearity
2. Week	Nonlinearity tests
3. Week	Evaluation of the nonlinearity
4. Week	Michaelis-Menten Kinetics
5. Week	One compartment model. I.V. administartion – Nonlinear behaviour
6. Week	One compartment model. absorption – Nonlinear behaviour
7. Week	Parallel first order and Michaelis-Menten Kinetics – I.V. administration
8. Week	Parallel first order and Michaelis-Menten Kinetics – absorption
9. Week	Two compartment model with Michaelis-Menten Kinetics
10. Week	Nonlinear binding
11. Week	Application methods I
12. Week	Nonlinear drugs
13. Week	Bioavailability and nonlinearity
14. Week	Calculation of bioavailability and nonlinearity
15. Week
16. Week

-- RECOMMENDED OR REQUIRED READING

Pharmacokinetics, M.Gibaldi, D.Perrier, Marcel Dekker, New York, 1982.

-- PLANNED LEARNING ACTIVITIES AND TEACHING METHODS

Lecture, Question & Answer, Demonstration, Drill - Practise

-- WORK PLACEMENT(S)

-- ASSESSMENT METHODS AND CRITERIA

	Quantity	Percentage
Mid-terms	0	0
Assignment	1	10
Exercises	0	0
Projects	1	30
Practice	0	0
Quiz	0	0
Contribution of In-term Studies to Overall Grade		40
Contribution of Final Examination to Overall Grade		60

-- WORKLOAD

Efficiency	Total Week Count	Weekly Duration (in hour)	Total Workload in Semester
Theoretical Study Hours of Course Per Week	14	2	28
Practising Hours of Course Per Week	0	0	0
Reading	6	5	30
Searching in Internet and Library	6	5	30
Designing and Applying Materials	0	0	0
Preparing Reports	0	0	0
Preparing Presentation	4	8	32
Presentation	4	10	40
Mid-Term and Studying for Mid-Term	1	7	7
Final and Studying for Final	1	8	8
Other			0
TOTAL WORKLOAD:			175
TOTAL WORKLOAD / 25:			7
ECTS:			7

-- COURSE'S CONTRIBUTION TO PROGRAM

NO	PROGRAM LEARNING OUTCOMES	1	2	3	4	5
1						X
2						X
3					X
4					X
5		X
6						X
7						X
8				X
9		X
10					X

Gazi University

Information Package

Programme Information

Search

GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR