GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
TRANSDERMAL AND TRANSMUCOSAL DRUG DELIVERY/FTE-3040
Course Title: TRANSDERMAL AND TRANSMUCOSAL DRUG DELIVERY
Credits 3 ECTS 7
Semester 1 Compulsory/Elective Elective
COURSE INFO
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- NAME OF LECTURER(S)
  Prof.Dr. Figen Tırnaksız, Assoc.Prof. Sibel İlbasmış Tamer
 -- WEB SITE(S) OF LECTURER(S)
  http://websitem.gazi.edu.tr/site/tfigen, www.websitem.gazi.edu.tr/site/ilbasmis/academic
 -- EMAIL(S) OF LECTURER(S)
  tfigen@gazi.edu.tr, ilbasmis@gazi.edu.tr
 -- LEARNING OUTCOMES OF THE COURSE UNIT
Learning the basic concepts and information about transdermal and transmucosal drug delivery systems.
Learning transdermal and transmucosal drug delivery systems formulations.
Learns the excipients used in transdermal and transmucosal drug delivery systems.
Learning contents of commercially available transdermal and transmucosal dosage forms.
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face
 -- PREREQUISITES AND CO-REQUISITES
  There is no prerequisite or co-requisite for this course.
 -- RECOMMENDED OPTIONAL PROGRAMME COMPONENTS
  There is no recommended optional programme component for this course.
 --COURSE CONTENT
1. Week  Main barriers for transdermal and transmucosal penetration Learning the ultra structure of skin and mucosal layers
2. Week  Advangates and disadvantages of transdermal and transmucosal delivery
3. Week  Mechanism of penetration
4. Week  Enhancement of penetration
5. Week  Prediction of penetration and available models
6. Week  Routes of penetration Permeation enhancement Understanding the mechanism of the skin penetration
7. Week  The mechanism of permeation enhancement The mathematical considerations of penetration
8. Week  Determination of permeability coefficient and calculations. Diffusion experiments, Franz type diffusion cells, design of diffusion cells for experime
9. Week  Reversible or irreversible effects of penetration enhancers. Rotating diffusion cells, microdialysis experiments, some new techniques in skin penetra
10. Week  Formulations of transdermal drug delivery systems (Matrix systems)
11. Week  Formulations of transdermal drug delivery systems (Membrane systems)
12. Week  The excipients and additives used in the formulations and thier roles
13. Week  Formulations of transmucosal drug delivery systems (Matrix systems)
14. Week  Formulations of transmucosal drug delivery systems (Membrane systems)
15. Week  
16. Week  
 -- RECOMMENDED OR REQUIRED READING
  - Encyclopedia of Pharmaceutical Technology, (Ed: Swarbrick, J., Boylan, J.C.), Vol.3., Marcel and Dekker, New York and Basel, 1992. - Transdermal
 -- PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
  Lecture, Question & Answer, Demonstration
 -- WORK PLACEMENT(S)
  NA
 -- ASSESSMENT METHODS AND CRITERIA
 
Quantity
Percentage
 Mid-terms
0
0
 Assignment
1
10
 Exercises
0
0
 Projects
1
30
 Practice
0
0
 Quiz
0
0
 Contribution of In-term Studies to Overall Grade  
40
 Contribution of Final Examination to Overall Grade  
60
 -- WORKLOAD
 Efficiency  Total Week Count  Weekly Duration (in hour)  Total Workload in Semester
 Theoretical Study Hours of Course Per Week
14
3
42
 Practising Hours of Course Per Week
0
 Reading
12
3
36
 Searching in Internet and Library
12
2
24
 Designing and Applying Materials
0
 Preparing Reports
9
2
18
 Preparing Presentation
7
3
21
 Presentation
1
1
1
 Mid-Term and Studying for Mid-Term
5
3
15
 Final and Studying for Final
6
3
18
 Other
0
 TOTAL WORKLOAD: 
175
 TOTAL WORKLOAD / 25: 
7
 ECTS: 
7
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2X
3X
4X
5X
6X
7X
8X
9X
10X