GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
Oxidative stress and antioxidant system/EBY-5040
Course Title: Oxidative stress and antioxidant system
Credits 2 ECTS 5
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Learning the free radicals, antioxidant defences, and oxidative stress.
Learning of diseases associated with free radicals and antioxidant using.
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face.
 --WEEKLY SCHEDULE
1. Week  Description of free radical, characteristics of radical reactions and free radical species
2. Week  Endogenous and exogenous sources of oxygen free radicals
3. Week  Targets of reactive oxygen species in the body, damage to proteins, lipids and DNA
4. Week  Damage to membrane: lipid peroxidation, mechanism and products of peroxide decomposition
5. Week  Enzymatic antioxidants: Superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx)
6. Week  Non-enzymatic antioxidants: β-carotene, vitamin C, Vitamin E and other compounds
7. Week  Description of oxidative stress, consequences of oxidative stress: adaptation, damage, repair and death
8. Week  Oxidative stress biomarkers measured in various biological materials
9. Week  Oxidative stress protocols for biomarkers used detection of free radical damage
10. Week  Diseases associated with free radicals, ischemia-reperfusion damage: cancer, and aging.
11. Week  Diseases associated with free radicals: cardiovascular disease, and diabetes.
12. Week  Diseases associated with free radicals: kidney damage, eye diseases, inflammatory diseases, neurodegerative diseases and others.
13. Week  The role of antioxidants in disease therapy, clinical trials
14. Week  The use of antioxidant vitamins and compounds in disease prevention, clinical trials
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
80
 Assignment
1
20
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
40
 Percentage of Final Exam to Total Score  
60
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
3
6
18
 Searching in Internet and Library
3
6
18
 Material Design and Implementation
0
 Report Preparing
1
3
3
 Preparing a Presentation
3
6
18
 Presentation
3
6
18
 Midterm Exam and Preperation for Midterm Exam
1
6
6
 Final Exam and Preperation for Final Exam
1
8
8
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
117
 TOTAL WORKLOAD / 25: 
4.68
 Course Credit (ECTS): 
5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2
3X
4X
5
6
7
8X
9
10
11X
12X
 -- NAME OF LECTURER(S)
   (Prof.Meral TORUN)
 -- WEB SITE(S) OF LECTURER(S)
   (http://websitem.gazi.edu.tr/site/mtorun)
 -- EMAIL(S) OF LECTURER(S)
   (mtorun@gazi.edu.tr)