GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
Bioenergetic and biological oxidation/EBY-3010
Course Title: Bioenergetic and biological oxidation
Credits 2 ECTS 5
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Know the biological energy transductions and thermodynamics laws
Know the Gibbs free energy in biochemical reactions and to learn the energy exchange in endergonic / exergonic reactions
know the bioenergetic biomolecules, oxidative phosphorylation and electron transport chain.
 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face
 --WEEKLY SCHEDULE
1. Week  Chemical reactions in living systems, energy requirements and energy cycle in living cells
2. Week  Laws of thermodynamics, Enthalpy / Entropy, Gibbs Free energy, endergonic / exergic biochemical reactions
3. Week  Functional groups and chemical reactivity in biological molecules, Electronegativity and electropositivity
4. Week  Problem solutions related to free energy change
5. Week  General classification and reaction mechanisms of enzyme-catalyzed reactions: oxidation-reduction reactions, breakdown and formation of carbon-carbo
6. Week  General classification and reaction mechanisms of enzyme-catalyzed reactions: molecular arrangement, group transfers and condensation reactions
7. Week  Biological oxidation, oxido-reduction potential
8. Week  Phosphorylation at substrate level, shuttle systems, introduction to oxidative phosphorylation
9. Week  Mitochonrial electron transport system (ETS) components, its structures and functions
10. Week  Complex protein components of ETS, radical formation
11. Week  ATP synthase enzyme complex and its function, chemiosmotic theory
12. Week  Brown adipose tissue, heat production and its regulation
13. Week  ETS inhibitors and their inhibitory mechanisms, regulation of oxidative phosphorylation, role of creatine phosphate system
14. Week  Stokrom P450 enzyme system and its biological functions
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
80
 Assignment
2
20
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
40
 Percentage of Final Exam to Total Score  
60
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
14
2
28
 Searching in Internet and Library
14
2
28
 Material Design and Implementation
0
 Report Preparing
3
2
6
 Preparing a Presentation
3
2
6
 Presentation
3
1
3
 Midterm Exam and Preperation for Midterm Exam
2
2
4
 Final Exam and Preperation for Final Exam
7
2
14
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
117
 TOTAL WORKLOAD / 25: 
4.68
 Course Credit (ECTS): 
5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1X
2
3X
4X
5
6
7X
8X
9X
10
11X
12X
 -- NAME OF LECTURER(S)
   (Prof. Yeşim ÖZKAN , PhD)
 -- WEB SITE(S) OF LECTURER(S)
   (http://websitem.gazi.edu.tr/site/yesim)
 -- EMAIL(S) OF LECTURER(S)
   (yesim@gazi.edu.tr)