GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
CELL BIOPHYSICS/BFZ-1080
Course Title: CELL BIOPHYSICS
Credits 3 ECTS 6
Semester 1 Compulsory/Elective Compulsory
COURSE INFO
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- NAME OF LECTURER(S)
  Prof. Dr. NESRİN SEYHAN, Assoc. Prof. Dr. AYŞE G. CANSEVEN KURŞUN, Assoc. Prof. Dr. GÖKNUR GÜLER ÖZTÜRK, Assist. Prof. Dr. BAHRİYE SIRAV ARAL
 -- WEB SITE(S) OF LECTURER(S)
  http://websitem.gazi.edu.tr/site/gozturk
 -- EMAIL(S) OF LECTURER(S)
  ggulerozturk@gmail.com
 -- LEARNING OUTCOMES OF THE COURSE UNIT
To learn about the basic structure and functions of the cell and cell membrane
To learn the intercellular and intracellular diffusion of ions and molecules, Fick's Laws.
Ionic Equilibrium: Nernst Equation
To learn the reasons of potential differences across the cell: Asymmetry, Phospholipid layer, ion concentration
To be informed about the Cell Membrane and Electrical Equivalent Circuit
To be informed about Electrical Stimulation
To be theoretically informed about Voltage Clamp and Patch Clamp
To prepare an oral presentation on the article survey proposed by the supervisor
 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face
 -- PREREQUISITES AND CO-REQUISITES
  There is no prerequisite or co-requisite for this course
 -- RECOMMENDED OPTIONAL PROGRAMME COMPONENTS
  There is no recommended optional programme component for this course.
 --COURSE CONTENT
1. Week  the basic structure and functions of the cell and cell membrane
2. Week  Diffusion and Fick's Laws
3. Week  Ionic Equilibrium: Nernst Equation
4. Week  The potential difference across the cell
5. Week  The potential difference across the cell 1. Asymmetry
6. Week  The potential difference across the cell 2. Phospholipid layer
7. Week  The potential difference across the cell 3. Ion Concentration
8. Week  Equivalent electrical circuit models of nerve cell
9. Week  Electrical Stimulus in nerve cells
10. Week  Hodgkin cycle
11. Week  The Voltage Clamp Technique
12. Week  The Patch Clamp Technique
13. Week  Overview of the course
14. Week  Final Exam
15. Week  
16. Week  
 -- RECOMMENDED OR REQUIRED READING
  - Purves D. et al; Neuroscience, Sinauer Associates Inc, USA, 2004. - Furman M.E. and Gallo F.P.; The Neurophysics of Human Behavior: Explorations at the Interface of the Brain, Mind, Behavior, and Information, CRC Pres, USA, 2000. - Pattabhi V., Gautham N.; Biophysics, Alpha Science, UK, 2002. - Polk C., Postow E.; Handbook of biological effects of electromagnetic fields, CRC Pres LLC, USA, 1996. - Çelebi G.; Biyofizik, Barış Yayınları, Cilt I, III. Baskı, İzmir, 2005. - Pehlivan F.; Biyofizik, Hacettepe – TAŞ, II. Baskı, Ankara, 2004.
 -- PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
  Lecture, Question & Answer, Demonstration, Drill - Practise
 -- WORK PLACEMENT(S)
  No
 -- ASSESSMENT METHODS AND CRITERIA
 
Quantity
Percentage
 Mid-terms
1
0
 Assignment
0
0
 Exercises
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Contribution of In-term Studies to Overall Grade  
50
 Contribution of Final Examination to Overall Grade  
50
 -- WORKLOAD
 Efficiency  Total Week Count  Weekly Duration (in hour)  Total Workload in Semester
 Theoretical Study Hours of Course Per Week
16
3
48
 Practising Hours of Course Per Week
0
 Reading
4
4
16
 Searching in Internet and Library
16
4
64
 Designing and Applying Materials
0
 Preparing Reports
0
 Preparing Presentation
4
3
12
 Presentation
2
3
6
 Mid-Term and Studying for Mid-Term
0
 Final and Studying for Final
1
4
4
 Other
0
 TOTAL WORKLOAD: 
150
 TOTAL WORKLOAD / 25: 
6
 ECTS: 
6
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1To prepare an oral presentation on the article survey proposed by the supervisorX
2Learning cell and electrical properties of cell, Equivalent electrical circuit model of membrane, Bio-Electric Potentials, Voltage-Clamp Technique.X
3Learning methods for generation of micro currents, Sources of Low Intensity Direct Current (LIDC) and effects of LIDC on soft tissues, Accelerating the recovery of injury by stationary micro currents and types of electrodes
4Learning piezoelectric structures in the body and ultrasound
5Learning physical properties of ultrasound, methods of ultrasound generation, ultrasound absorbtion of tissues, differences of kidney, lipids, muscle, liver, blood, plasma and bone tissues in absorption of ultrasound, characteristic impedance of tissues and penetration of ultrasound, Diagnostic and therapeutic ultrasound, ultrasound cavitation effect and using in researches, Micromassage effect
6Learning Stimulus of tissue by electric current; Injury current in tissues; Sonic characteristics in tissues, Characteristic impedance of tissues; Thermal effects of ultrasound; Use of ultrasound in medicine; Diagnostic, therapeutic and surgical ultrasound; Doppler ultrasound; Infrasound.X
7Learning Equivalent electrical circuit models of circulatory system; Factors affecting on friction in the circulatory system; Factors of blood flow in vessels; Relation of vessel resistance and pressure difference; Stoke’s law; Bernouilli law; Relations between velocity, flow and resistance; Vessel’s radius in the internal frictional flow; Kinetic energy factor in vessels; Factors affecting on the circulation in exercise.
8Learning reason of biological potential difference: Asymmetry, the role of phospholipids on the formation of cell potential, the role of ion concentration difference on the formation of cell potential, equivalent electrical circuit models of nerve cell, stimulus in nerve cell, local stimulus, Hodkin cycle.X
9To gain the ability of presentation skills and scientific queries.X
10Learning sonic characteristics of biological tissues, Biophysics of Hearing, Ear as a transducer, Biomaterials, properties of Biomaterials and metallic implants, reasons and solutions of implant corrosion inside the body
11Learning Conductivity of tissues, dielectric properties of tissues, electrosurgery, Microcurrents in accelerating the recovery of bone injury and methods for application of microcurrents
12Learning Laser, its physical characteristics, formation mechanism, and effects, interactions with biologic mediums, types (argon, CO2 ,YAG, helium) and applications.
13To learn theory and applications of Biomagnetic Fields.
14Learning Biophysics and Theory of Electromagnetic Field
15Learning Dosimetry, Scaling, Determination of applied Magnetic Field values on living beings, modelling studies and scaling factor from animal to human.