GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
BIOACTIVE NITROGEN-CONTAINING NATURALCOMPOUNDS/FRG-1240
Course Title: BIOACTIVE NITROGEN-CONTAINING NATURALCOMPOUNDS
Credits 2 ECTS 6
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
To have an information about the nitrogen-containing compounds, their chemical structures, specifications and classification.
To have a knowledge for the bioactive amins, cyanogenetic and noncyanogenetic glycosides, alkaloids and their sources alongwith their pharmaceutical p
To have an information about the properties of natural anticancer compounds and their role in therapy
To have an information about the determination of cytotoxic compounds found in natural sources
To have an information about natural anticancer compounds named as wisdom drugs prepared by using biotechnological methods
To have an information about the derivatives of anticancer compounds used in therapy alongwith their side effects.
To have an information about the natural chemoprevantives.
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face by using power point document.
 --WEEKLY SCHEDULE
1. Week  General information for the secondary metabolites and nitrogen–containing compounds
2. Week  Alkaloids and their chemical structures and specifications, Biosynthesis of alkaloids and their role for natural sources, their importance in chemota
3. Week  Classification of alkaloids according to their biological activities, Preparation of the derivatives of alkaloids used in therapy
4. Week  Bioactive alkaloids in animals and marine organisms
5. Week  General information for cancer types, treatments and terms related cancer, The definition of chemotherapy and the role in therapy
6. Week  Mechanisms of the effectives for the compounds used in chemotherapy
7. Week  Determination of cytotoxic compounds found in natural sources In vitro and İn vivo screening tests
8. Week  Development of the active constituents from the cytotoxic compounds
9. Week  Anticancer compounds from microorganisms
10. Week  Vinca alkaloids, Podophyllotoxine and its derivatives Camptothecine and its derivatives; Taxol and its derivatives
11. Week  Natural anticancer compounds obtained by using biotechnological methods, wisdom drugs
12. Week  Immunostimulant and immunosuppressive natural products
13. Week  Natural chemoprevantives.
14. Week  Presentation and discussions of the homeworks belonged to pharmaceuticals sold in market prepared by the students
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
50
 Assignment
1
50
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
3
2
6
 Searching in Internet and Library
2
4
8
 Material Design and Implementation
0
 Report Preparing
3
3
9
 Preparing a Presentation
3
3
9
 Presentation
1
1
1
 Midterm Exam and Preperation for Midterm Exam
7
6
42
 Final Exam and Preperation for Final Exam
8
6
48
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
151
 TOTAL WORKLOAD / 25: 
6.04
 Course Credit (ECTS): 
6
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1Has up to date information in the field of Pharmacognosy and Phytotherapy based on the knowledge and skills from his/her pharmacy education.X
2Gives importance to the professional development and lifelong learning, deepen his/her knowledge by following national/international developments by using printed publications, technological tools and databases.X
3Is in communication with his/her colleagues and other professional groups in the health field, presents his/her ideas on current issues to these people and society orally/written.X
4Performs scientific studies in common areas with different disciplines by using computer, necessary technical equipment and devices.X
5Evaluates and interprets the results of theoretical and experimental studies statistically.X
6Designs a study in the field of Pharmacognosy, work independently or as a team member, interpret the results critically and present them in a report.X
7Collects data on topics such as pharmacognosy, phytopharmacy and ethnobotany, takes part in national and international studies to interpret and advertise these data.X
8Presents a Pharmacognosic study, he/she participated or conducted, in a scientific meeting, writes an article and publishes it in a journal.X
9Has information about production, properties, quality and analysis of herbal medicine, drug preparation, herbal teas and medicinal plants.X
10Knows secondary metabolites in plants, their occurence, their production by biotechnology, identifications and isolations.X
11Has knowledge on the biological activities on medicinal plants.X
12Does analysis and isolation by using various chromatographic techniques.X
13Does qualitative and quantitative analysis on plant, drug and preparations by using various instrumental techniques.X
14Has information about pharmacopoeia analysis and pharmacognosic methods.X
15Knows the structures of natural products used in therapy, their utilization and preparations, can do consulting on their use.X
16Has information about important medicinal products of Turkey such as Opium alkaloids and volatile oils.X
17Reads English publications in the field of Pharmacognosy and Phytotherapy, compiles these studies and gives presentation within the scope of “Seminar” course.X
 -- NAME OF LECTURER(S)
   (Prof.Dr. Bilge ŞENER)
 -- WEB SITE(S) OF LECTURER(S)
   (https://abs.gazi.edu.tr/bilgesen)
 -- EMAIL(S) OF LECTURER(S)
   (bilgesen@gazi.edu.tr ; bilgesener11@gmail.com)