GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
PRACTICES IN ANALYTICAL TOXICOLOGY/FTO-1011
Course Title: PRACTICES IN ANALYTICAL TOXICOLOGY
Credits 3 ECTS 7.5
Course Semester 2 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Have skills in practice of determinations of toxic chemicals and their metabolites in different compartments
Development of the ability to use various analytical methods
 -- MODE OF DELIVERY
  The mode of delivery of this course is Face to face
 --WEEKLY SCHEDULE
1. Week  Principles of extraction procedures of toxic substances from biological samples in Analytical Toxicology
2. Week  Principles of extraction procedures of toxic substances from biological samples in Analytical Toxicology
3. Week  Principles of extraction procedures of toxic substances from biological samples- student practice
4. Week  Principles of spectrophotometric analysis
5. Week  Principles of spectrophotometric analysis
6. Week  Determination some organochlorine pesticides in human milk by GC)-student practice
7. Week  Determination some barbituric acids from urine by thin layer chromatograph-student practice
8. Week  Laboratory work and midterm exam
9. Week  Cleanup techniques and elementary analysis by atomic absorption spectroscopy and student practice
10. Week  Cleanup techniques and elementary analysis by atomic absorption spectroscopy and student practice
11. Week  Determination of nicotine and cotinine levels in smoker and nonsmoker subjects by HPLC-student practice
12. Week  Determination of cyclophosphamide in urine by GC-MS-student practice
13. Week  Immunoassay techniques for drugs I
14. Week  Immunoassay techniques for drugs II
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
25
 Assignment
0
0
 Application
1
25
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
0
 Weekly Tutorial Hours
14
3
42
 Reading Tasks
14
5
70
 Searching in Internet and Library
8
2
16
 Material Design and Implementation
3
3
9
 Report Preparing
5
2
10
 Preparing a Presentation
5
3
15
 Presentation
5
4
20
 Midterm Exam and Preperation for Midterm Exam
1
3
3
 Final Exam and Preperation for Final Exam
1
4
4
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
189
 TOTAL WORKLOAD / 25: 
7.56
 Course Credit (ECTS): 
7.5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1The ability to understand the principles of toxicologyX
2The ability to design and conduct experiments, to evaluate and interpret critically toxicity data.X
3Effectively use acquired laboratory skills in toxicological researchX
4The ability to use necessary techniques and modern analysis tools for toxicological analysis practiceX
5Undertake complex toxicology data analysis, the ability to analyze, synthesize and evaluate new ideasX
6The ability to work effectively as an individual, in teams, and in multidisciplinaryX
7Display excellence and innovation in problem-solving skills, demonstrate a sophisticated level of interpretation and the ability to communicate both orally and in writing at a high level of proficiencyX
8The ability to evaluate and to apply human health risks caused by drugs and other chemicals. Perform complicated chemical risk assessments.X
9The ability of monitoring, searching and evaluating the advers drug effectsX
10To know the principles of first aid and treatment of poisoning and the ability to make the effective guidanceX
11Be able to describe thoroughly the chemical concentration/dose to the observed toxicity effects and to understand the mode of action of the chemicals or its metabolites in living organismsX
12To understand the mechanisms of the production of the free radicals, oxidative stress and the relation of the radicals to the xenobiotic metabolism and their toxicological significanceX
13Gaining knowledge on the immune system, effects of the xenobiotics on the immune system, pathological alterations of the biological system due to these alterations.
14To achieve current knowledge and awareness with regards to the national and international regulation of chemical, physical and biological agents and use of toxicology data in regulation approach.X
15To learn application and evaluation of toxic effects of chemicals by in vivo and in vitro test systems.X
 -- NAME OF LECTURER(S)
   (Prof.Dr. İsmet ÇOK , Prof.Dr. Bensu Karahalil)
 -- WEB SITE(S) OF LECTURER(S)
   (websitem.gazi.edu.tr/site/ismetc , w3.gazi.edu.tr/web/bensu)
 -- EMAIL(S) OF LECTURER(S)
   (ismetc@gazi.edu.tr , bensuka@gmail.com)