GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION

TOXIC EFFECTS EVALUATION AND ASSESSMENT METHODS/FTO-1050

Course Title:	TOXIC EFFECTS EVALUATION AND ASSESSMENT METHODS
Credits	3	ECTS	7.5
Course Semester	1	Type of The Course	Compulsory

COURSE INFORMATION

-- (CATALOG CONTENT)

-- (TEXTBOOK)

-- (SUPPLEMENTARY TEXTBOOK)

-- (PREREQUISITES AND CO-REQUISITES)

-- LANGUAGE OF INSTRUCTION

Turkish

-- COURSE OBJECTIVES

-- COURSE LEARNING OUTCOMES

Understand the principles of toxicity testing and gaining skills in evaluation and interpretation of data

-- MODE OF DELIVERY

The mode of delivery of this course is Face to face

--WEEKLY SCHEDULE
1. Week	Purpose of chemical safety evaluation
2. Week	International guidelines on toxicity tests and evaluation
3. Week	The rationale for acute toxicity testing
4. Week	Methodology of acute oral, dermal and inhalation toxicity studies
5. Week	Alternative acute oral and dermal toxicity methods
6. Week	The rationale for sub-acute and sub-chronic toxicity testing
7. Week	Methodology of sub-acute and sub-chronic toxicity studies
8. Week	Midterm exam
9. Week	Methodology of immunotoxicity/neurotoxicity studies
10. Week	The rationale for chronic toxicity/carcinogenicity testing
11. Week	Methodology of chronic toxicity/carcinogenicity testing
12. Week	Homework
13. Week	The rationale for mutagenicity testing
14. Week	Methodology of bacterial mutagenicity, chromosome aberration and micronucleus tests
15. Week	Methodology of reproductive/developmental toxicity studies
16. Week	Final exam

-- TEACHING and LEARNING METHODS

-- ASSESSMENT CRITERIA

	Quantity	Total Weighting (%)
Midterm Exams	1	25
Assignment	1	25
Application	0	0
Projects	0	0
Practice	0	0
Quiz	0	0

Percent of In-term Studies		50
Percentage of Final Exam to Total Score		50

-- WORKLOAD

Activity	Total Number of Weeks	Duration (weekly hour)	Total Period Work Load
Weekly Theoretical Course Hours	14	3	42
Weekly Tutorial Hours			0
Reading Tasks	3	10	30
Searching in Internet and Library	4	10	40
Material Design and Implementation			0
Report Preparing			0
Preparing a Presentation	2	10	20
Presentation	2	10	20
Midterm Exam and Preperation for Midterm Exam	1	12	12
Final Exam and Preperation for Final Exam	1	24	24
Other (should be emphasized)			0
TOTAL WORKLOAD:			188
TOTAL WORKLOAD / 25:			7.52
Course Credit (ECTS):			7.5

-- COURSE'S CONTRIBUTION TO PROGRAM

NO	PROGRAM LEARNING OUTCOMES	1	2	3	4	5
1	The ability to understand the principles of toxicology					X
2	The ability to design and conduct experiments, to evaluate and interpret critically toxicity data.					X
3	Effectively use acquired laboratory skills in toxicological research		X
4	The ability to use necessary techniques and modern analysis tools for toxicological analysis practice		X
5	Undertake complex toxicology data analysis, the ability to analyze, synthesize and evaluate new ideas				X
6	The ability to work effectively as an individual, in teams, and in multidisciplinary			X
7	Display excellence and innovation in problem-solving skills, demonstrate a sophisticated level of interpretation and the ability to communicate both orally and in writing at a high level of proficiency	X
8	The ability to evaluate and to apply human health risks caused by drugs and other chemicals. Perform complicated chemical risk assessments.			X
9	The ability of monitoring, searching and evaluating the advers drug effects		X
10	To know the principles of first aid and treatment of poisoning and the ability to make the effective guidance	X
11	Be able to describe thoroughly the chemical concentration/dose to the observed toxicity effects and to understand the mode of action of the chemicals or its metabolites in living organisms			X
12	To understand the mechanisms of the production of the free radicals, oxidative stress and the relation of the radicals to the xenobiotic metabolism and their toxicological significance	X
13	Gaining knowledge on the immune system, effects of the xenobiotics on the immune system, pathological alterations of the biological system due to these alterations.	X
14	To achieve current knowledge and awareness with regards to the national and international regulation of chemical, physical and biological agents and use of toxicology data in regulation approach.			X
15	To learn application and evaluation of toxic effects of chemicals by in vivo and in vitro test systems.					X

-- NAME OF LECTURER(S)

(Prof.Sema BURGAZ)

-- WEB SITE(S) OF LECTURER(S)

()

-- EMAIL(S) OF LECTURER(S)

(burgaz@gazi.edu.tr)

Gazi University

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GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR