GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
DRUG BIOTRANSFORMATION/FKİ-3040
Course Title: DRUG BIOTRANSFORMATION
Credits 2 ECTS 5
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Have gained knowledge about metabolic enzymes. .
Have gained knowledge about Michael-Menten approach.
Be able to understand Phase I and Phase II Enzymes.
Be able to predict metabolism of drugs.
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face
 --WEEKLY SCHEDULE
1. Week  Cytochrome P450 monooxygenases
2. Week  Cytochrome P450 monooxygenases
3. Week  Flavin monooxygenases
4. Week  Epoxide hydrolases
5. Week  Monoamine oxidases
6. Week  Xanthine oxidases/Aldehyde oxidases
7. Week  Aldehyde dehydrogenases/Aldo-keto reductases
8. Week  Alcohol dehydrogenases
9. Week  Carbonyl reductases
10. Week  Prostaglandin H Synthase
11. Week  Glutathione peroxidase
12. Week  Glutathione S-transferase/UDP glucuronosyltransferase
13. Week  Sulfotransferase/Methyltransferase
14. Week  Acetyltransferase/Carboxytransferase/Amidase
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
35
 Assignment
0
35
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
3
30
 Percent of In-term Studies  
50
 Percentage of Final Exam to Total Score  
50
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
14
2
28
 Searching in Internet and Library
10
2
20
 Material Design and Implementation
0
0
0
 Report Preparing
3
3
9
 Preparing a Presentation
3
4
12
 Presentation
1
1
1
 Midterm Exam and Preperation for Midterm Exam
3
4
12
 Final Exam and Preperation for Final Exam
3
5
15
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
125
 TOTAL WORKLOAD / 25: 
5
 Course Credit (ECTS): 
5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1Applies current knowledge in the field of Pharmaceutical Chemistry with the related field.X
2Comprehends the interdisciplinary interaction related to the field of Pharmaceutical Chemistry and interprets the information to integrate and create new information.X
3Reaches the information about the research topic from national and international resources, compiles and interprets them.X
4Prepares scientific reports of his/her research activities.X
5Uses laboratory equipment including computer which is required during experimental research.
6Presents the results of the work at national or international meetings organized in the field of expertise.X
7Knows the importance of ethical principles and ethical rules for individual and society, behaves ethically.
8Applies advanced organic chemistry knowledge and chemical synthesis procedures.
9Performs experiments using separation and purification methods.
10Elucidates molecular structures using spectral analysis.
11Evaluates the behavior of the drug in biological systems and proposes a new chemical molecule for drug design.X
12Has the knowledge about qualitative and quantitative analysis methods of drugs and applies them.
13Knows advanced organic chemistry, behavior of drugs in biological systems, qualitative-quantitative and spectral structure analysis methods of drugs, including separation and purification methods.X
 -- NAME OF LECTURER(S)
   (Prof. Dr. Erden Banoğlu)
 -- WEB SITE(S) OF LECTURER(S)
   ( http://websitem.gazi.edu.tr/site/banoglu)
 -- EMAIL(S) OF LECTURER(S)
   ( banoglu@gazi.edu.tr)