GAZI UNIVERSITY INFORMATION PACKAGE - 2019 ACADEMIC YEAR

COURSE DESCRIPTION
Defence Systems Protecting from Free Radicals/EBY-2080
Course Title: Defence Systems Protecting from Free Radicals
Credits 2 ECTS 5
Course Semester 1 Type of The Course Elective
COURSE INFORMATION
 -- (CATALOG CONTENT)
 -- (TEXTBOOK)
 -- (SUPPLEMENTARY TEXTBOOK)
 -- (PREREQUISITES AND CO-REQUISITES)
 -- LANGUAGE OF INSTRUCTION
  Turkish
 -- COURSE OBJECTIVES
 -- COURSE LEARNING OUTCOMES
Understanding properties of intracellular and extracellular antioxidants.
Learning the use of antioxidants in the prevention and treatment of diseases.
 -- MODE OF DELIVERY
  The mode of delivery of this course is face to face.
 --WEEKLY SCHEDULE
1. Week  Description of antioxidant, properties and classification
2. Week  Antioxidant defence enzymes:Catalases, reaction mechanism and peroxidatic activity
3. Week  Antioxidant defence enzymes: Glutathione peroxidase family, cooperation of glutathione peroxidase and catalase in the removal of hydrogen peroxide
4. Week  Antioxidant defence enzymes:Superoxide dismutases, physiologic importance of superoxide dismutases, dismutation reactions
5. Week  Low-molecular mass antioxidant molecules:Vitamin E, chemistry of vitamin E, evidence for an antioxidant effect of vitamin E
6. Week  Low-molecular mass antioxidant molecules:Vitamin C, antioxidant and pro-oxidant effects of vitamin C
7. Week  Low-molecular mass antioxidant molecules: Carotenoids, metabolic roles of carotenoids, carotenoids as antioxidant
8. Week  Low-molecular mass antioxidant molecules: Glutathione, scavenging of reactive species by gluathione, glutathione biosynthesis and degradation
9. Week  Other antioxidant molecules: bilirubin, sex hormons, melatonin, lipoik asid.
10. Week  Other antioxidant molecules: coenyzme Q, uric acid, melanin
11. Week  Origin of oxidative stress in disease, consequences and significance of oxidative stress in disease
12. Week  Antioxidants and treatment of disease, therapeutic antioxidants
13. Week  A common link between oxidative damage and aging, altered antioxidant levels
14. Week  The importance of antioxidants as a dietary factors in nutrition
15. Week  
16. Week  
 -- TEACHING and LEARNING METHODS
 -- ASSESSMENT CRITERIA
 
Quantity
Total Weighting (%)
 Midterm Exams
1
70
 Assignment
1
30
 Application
0
0
 Projects
0
0
 Practice
0
0
 Quiz
0
0
 Percent of In-term Studies  
60
 Percentage of Final Exam to Total Score  
40
 -- WORKLOAD
 Activity  Total Number of Weeks  Duration (weekly hour)  Total Period Work Load
 Weekly Theoretical Course Hours
14
2
28
 Weekly Tutorial Hours
0
 Reading Tasks
3
6
18
 Searching in Internet and Library
3
6
18
 Material Design and Implementation
0
 Report Preparing
1
3
3
 Preparing a Presentation
3
6
18
 Presentation
3
6
18
 Midterm Exam and Preperation for Midterm Exam
1
6
6
 Final Exam and Preperation for Final Exam
1
6
6
 Other (should be emphasized)
0
 TOTAL WORKLOAD: 
115
 TOTAL WORKLOAD / 25: 
4.6
 Course Credit (ECTS): 
5
 -- COURSE'S CONTRIBUTION TO PROGRAM
NO
 PROGRAM LEARNING OUTCOMES
1
2
3
4
5
1Explains the basic biochemical reactions, molecular mechanisms from cell to organism, associates them with each other, discusses and interprets the structure-function relationshipX
2Define the basic concepts and issues related to biochemistry and relate this knowledge to other disciplines.X
3Applies the basic experimental techniques and protocols safely in the laboratory.
4Design original scientific research, interpret experimental dataX
5Presents his / her work through written, oral and visual presentations. Creates new experimental protocols and evaluates statistical data.X
6Comprehends the principles, quality control and reliability of analytical devices used in both routine clinical laboratories and research laboratories.
7Interprets the normal functioning mechanism of the organism on a biochemical basis.X
8Applies the methods used in routine biochemistry laboratories and interprets the results clinically.
9Understands the importance of biochemistry discipline for public health and share information with the public. Carry out scientific studies with ethical responsibiltyX
10Applies working principles in accordance with the disciplinary and interdisciplinary professions.
11Follow the scientific literature and draw conclusions, associate them with their researches and use them in their researches.X
 -- NAME OF LECTURER(S)
   (Prof.Meral TORUN)
 -- WEB SITE(S) OF LECTURER(S)
   (http://websitem.gazi.edu.tr/site/mtorun)
 -- EMAIL(S) OF LECTURER(S)
   (mtorun@gazi.edu.tr)